SyDERMA® is meant for external use only and should be applied in a "rub on" fashion to the skin surface where additional protection is desired. It is important that the skin surface be washed and thoroughly dried prior to applying SyDERMA®. SyDERMA® should be applied directly to the skin surface from the bottle or dispenser, usually into the palm of one hand. It should then be rubbed onto the other hand or other skin surface. An amount of SyDERMA® approximately the size of a nickel coin will cover an area the size of an average sized pair of hands. Larger sized areas of skin surface would of course require larger amounts of SyDERMA®.

It is very important to apply SyDERMA® thoroughly over the entire surface of the skin area to be protected, paying special attention to folds and crevices in the skin surface, and between fingers, and especially areas such as the cuticles and under fingernails. Allow approximately one to three minutes for SyDERMA® to dry. SyDERMA® must be completely dry in order for its ingredients to have maximum effectiveness. Incomplete drying may reduce effectiveness. Do not wash or scrub the skin until SyDERMA® is completely dry. Once complete drying has occurred, each application of SyDERMA® will provide protection for intact skin for a period of 4 to 6 hours. Gloves may be applied as soon as SyDERMA® is dry to the touch. SyDERMA® does not interfere with the sense of touch and will not compromise dexterity. It is not recommended that SyDERMA® be applied to the entire body, or on an area of infection, deep wounds or puncture wounds, or animal bites. It is intended only for areas of the body that are exposed to harmful contaminants (i.e. hands, arms, hands and arms; torso for incontinence, legs, feet).

Note: Avoid exposure at all times of any unprotected skin area to potential irritants! Apply up to 3 times daily, as needed.